|Zuo Laboratory, MCD Biology, UCSC|
Zuo Lab Research
The human brain is an extremely complicated organ, in which billions of neurons make trillions of connections. Synapses are the principal sites at which neurons communicate with one another. Experience-dependent modification of synaptic structure and function provides a cellular mechanism for learning and memory, while abnormal synaptic connections are hallmarks of many neurological and psychiatric disorders. My laboratory studies how the neuronal circuitry is rewired during learning and memory formation, and investigates the cellular mechanisms underlying structural changes of synapses under both physiological and pathological conditions. We utilize the following tools while undertaking this research.
To learn more about our research, visit the following web pages, which provide more detailed about specific research projects and collaborations with other investigators.
Project 1: Synapse remodeling in learning and memory formation
Project 2: Cellular mechanism of spine dynamics
Project 3: Glia's role in synapse plasticity
We are grateful for the generous research support provided by the following funding agencies: the National Institute on Aging, the National Institute of Mental Health, the Alfred P. Sloan Foundation, the American Federation for Aging, the Ellison Medical Foundation, the DANA Foundation and the W.M. Keck Foundation.
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